Copa Airlines currently operates 18 flights per week between Panama City and Cartagena. The aircraft used are the Boeing 737-700 and Boeing 737-800, with capacity for 124 and 154 passengers respectively.
See also: Copa resumes operations to Boston.
Due to the start of the high season, the company will increase to 20 weekly services in November and 21 in December. The three daily operations will be in operation until late February.
Schedule between Panama and Cartagena – Copa Airlines
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| Flight | From | ETD | To | ETA |
| CM 161 | Panamá (PTY) | 7:33 a.m. | Cartagena (CTG) | 8:44 a.m. |
| CM 160 | Cartagena (CTG) | 9:29 a.m. | Panamá (PTY) | 10:48 |
| Flight | From | ETD | To | ETA |
| CM 304 | Panamá (PTY) | 11:52 a.m. | Cartagena (CTG) | 1:01 p.m. |
| CM 305 | Cartagena (CTG) | 3:49 p.m. | Panamá (PTY) | 5:13 p.m. |
See also: Copa Airlines increases flights to Buenos Aires.
| Flight | From | ETD | To | ETA |
| CM 202 | Panamá (PTY) | 9:38 p.m. | Cartagena (CTG) | 10:48 p.m. |
| CM 203 | Cartagena (CTG) | 6:57 a.m. | Panamá (PTY) | 8:21 a.m. |
Flight frequency (from December)
- CM 160/161: daily.
- Flight CM 304/305: daily.
- CM 202/203: daily.
Copa Airlines offers 11 routes to Colombia from the Panamanian capital (Armenia, Barranquilla, Bucaramanga, Bogota, Cali, Cartagena, Cucuta, Medellin, Pereira and San Andres Island, Santa Marta). According to Cirium, the company operates more than 700 flights between both countries.
